European Application Engineers Hamamatsu Photonics Massy, Ile-de-France, France
Abstract: Confocal fluorescence microscopes are indispensable tools in biological research, offering high-resolving power and depth imaging capabilities. However, because researchers have been unsatisfied with their high costs, installation complexity, and laser-induced specimen damage, their widespread adoption has been hindered.
To address these challenges, Hamamatsu Photonics has developed the MAICO® MEMS, a new independent confocal unit that researchers can easily plug into their inverted microscope to achieve confocal fluorescence imaging. This compact, bench-top solution does not require other devices such as cameras, filters, or lasers. In addition, it offers high-speed, high-sensitivity imaging and a compact design with simultaneous multiband observations without bleed-through.
We will present examples showcasing confocal imaging of the H9c2 cell nucleus, mitochondria, cell membrane, and actin filament with different dyes and channels. This will also include results of the cells and neuron structure in the thick section of a mouse brain. With these examples, we illustrate the ease of transitioning from wide-field to confocal microscopy, making it an ideal choice for cellular investigations and ion channel studies.
