Transforming Cardiovascular Research with CellXpress.ai: Unleashing the Potential of 3D Biology in Automated High-Throughput Cardioids for Drug Discovery and Toxicity Screening.
Sr. Manager of Assay Development Molecular Devices San Jose, California, United States
Cardiovascular Disease (CVD) remains a significant global health concern, accounting for 32% of all mortalities. The lack of reliable and representative human heart in vitro models poses a major challenge in drug discovery, hindering the development of effective treatments.
Join this tutorial and discover a fully automated high-throughput platform for culturing induced pluripotent stem cells (iPSC) and differentiating them into 3D self-organizing cardiac organoids (Cardioids). This cutting-edge platform ensures reproducible Cardioid quality through automated handling and continuous image-based monitoring. With minimal human intervention and low Cardioid variability, researchers can efficiently upscale and mature Cardioids in screening-ready plates. Utilizing high-throughput functional imaging, this platform enables modeling of cardiomyopathies and assessment of cardiotoxicity. Attend this tutorial to explore the potential of iPSC-derived 3D Cardioids in CVD drug discovery and toxicity screening, and gain insight into the future of cardiovascular research with the CellXpress.ai™ Automated Cell Culture System.